A key pathway, called wnt, that drives tumor growth in bile duct cancer has been discovered and a new class of experimental drug could help the patients with bile duct cancer. A key pathway, called ...

Hepatic synthesis of bile acids is the primary pathway for cholesterol catabolism. The cholesterol 7α-hydroxylase enzyme (encoded by CYP7A1) represents the rate-limiting step of the multi-enzymatic ...

It's no secret that a high-fat, high-cholesterol "junk food" diet has been linked to major health problems, including high blood cholesterol and the buildup of plaques in the arteries, known as ...

Examining gut health from a different angle, Flinders University’s Associate Professor Robyn Meech is looking at what can trigger colon cancer – and she believes bile acids may provide a significant ...

Crosstalk between the Notch signaling pathway and Caudal-related homeobox 2 (Cdx2) has important roles in the development of Barrett’s esophagus (BE). We investigated the expression and function of ...

Pathway is now the first and only FDA-approved companion diagnostic for identifying HER2-positive biliary tract cancer patients eligible for treatment with Ziihera. The FDA has approved a label ...

Stage 4 bile duct cancer is the most advanced stage of this disease. Treatment involves managing symptoms and improving quality of life. Bile duct cancer is a rare type of cancer that affects the bile ...

Patients with bile duct cancer could be helped by a new class of experimental drug, a laboratory study has shown. Experimental drugs that block the wnt pathway are already being tested in patients ...

Tsukuba, Japan—Bile ducts are pathways that carry hepatocyte-produced bile from the liver to the small intestine. In the human fetal liver, bile ducts are formed from bile duct epithelial cells ...

BBPH, bear bile powder high dose; BBPL, bear bile powder low dose; DSS, dextran sulfate sodium; NC, normal control; 5-ASA, 5-Amino salicylic acid. Ulcerative colitis (UC) is a chronic autoimmune ...