A statistical mechanical theory on the effects of denaturant on the helix–coil transition of polypeptides was developed. In the proposed theory, unfolding agents were assumed to interact with the ...

Bradbury, E. M., and Rattle, H. W. E., Polymer (in the press). Bradbury, E. M., Crane-Robinson, C., Goldman, H., and Rattle, H. W. E., Biopolymers (in the press ...

The biological functions of coiled coils generally depend on efficient folding and perfect pairing of their α-helices. Dynamic changes in the helical registry that lead to staggered helices have only ...

Membrane proteins play a pivotal role in various cellular functions and are key targets for pharmaceutical interventions. In fact, approximately 60% of drugs currently available on the market target ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 78, No. 10, [Part 2: Biological Sciences] (Oct., 1981), pp. 6101-6105 (5 pages) We have determined the rates of ...