Novel Treatment Targets in Sarcoma: More Than Just the GIST MYC has proven to be a highly potent oncoprotein when it is overexpressed, but is also a pleiotropic transcription factor essential for ...

“MYC is one of the most notorious cancer-causing genes, and tumors driven by MYC overexpression are often among the most aggressive and difficult to treat." The trial, which will begin later this year ...

Northwestern Medicine investigators have discovered a new combination approach that may improve the efficacy of MYC inhibitor drugs for treating aggressive and treatment-resistant cancers, according ...

The MYC oncogene family plays an important role in neoplastic disease, and has been extensively studied over decades. Evidence showing the N-terminal and C-terminal regions of MYC can function as a ...

In healthy cells, the protein MYC helps guide the process of transcription, in which genetic information is converted from DNA into RNA and, eventually, into proteins. However, the shapeless protein ...

Cancer researchers have discovered surprising new functions for a protein called MYC, a powerful oncogene that is estimated to drive the development of almost half a million new cancer cases in the US ...

A new review in Genes and Diseases explores the central role of MYC, a master regulatory protein, in the development and progression of cancer, spotlighting its potential as a multidimensional ...

During an episode of your favorite true crime drama, you’ve probably seen the detective piece together clues with all evidence pointing neatly to “Suspect A”. But there’s something that doesn’t quite ...

Seals give birth only when conditions are right. After mating, a female seal can delay implantation of the embryo in the ...