New findings suggest sex-specific immune responses in Alzheimer’s, as female microglia show heightened interferon signaling ...
More than 7 million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's ...
“This is a paradigm shift,” says Donn Van Deren, PhD, postdoctoral research fellow at the University of Pennsylvania, who ...
Researchers led by those at the University of Rochester, US, found that immune cells in the brain, known as microglia, act ...
An international team of scientists has uncovered the vital role of microglia, the immune cells in the brain that acts as its dedicated defense team, in early human brain development. By incorporating ...
A new study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer's pathology in other ways. A rare but potent genetic ...
During most eye infections or injuries, neutrophils, immune cells found in the blood, are usually the first line of defense. However, researchers at the Flaum Eye Institute and Del Monte Institute for ...
In Alzheimer’s disease, microglia act as a double-edged sword. They can either protect the brain or worsen the damage, depending on their activation state. Inflammatory activation harms healthy ...
Mouse microglia got a genetic tune-up. On 9 June in Nature Aging, researchers led by Warren G. Tourtellotte at Cedars-Sinai Medical Center in Los Angeles reported that expressing human ...
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